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Name: Tramadol (2-[(dimethylamino)methyl]-1-(3methoxyphenyl)cyclohexanol)
Type: Opioid
AKA: Tramadol
![Tramadol (2-[(dimethylamino)methyl]-1-(3methoxyphenyl)cyclohexanol) image](https://grammasearch.com/dev/v2/img/tramadol.jpg)
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
![Tramadol (2-[(dimethylamino)methyl]-1-(3methoxyphenyl)cyclohexanol) image](/dev/v2/pages/pubchem_images/33741.png)
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IV. History
Tramadol, a synthetic opioid analgesic, was first introduced in the 1970s. It was developed to manage moderate to severe pain with a lower potential for abuse compared to other opioids. Tramadol's introduction marked a significant advancement in pain management. Its use has been associated with dependence and regulatory controls to address abuse potential.
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V. Legal Information
Tramadol is a prescription opioid used for pain management. In the U.S., it is classified as a Schedule IV controlled substance, indicating a recognized potential for abuse but lower than Schedule I drugs. Globally, tramadol's legal status varies, with some countries placing it under strict regulation due to its abuse potential. Trends are shifting towards tighter control to mitigate misuse and dependency issues. [Source: UNODC].
US Federal Schedule - IV
Schedule IV drugs, substances, or chemicals are defined as drugs with a low potential for abuse and low risk of dependence. Some examples of Schedule IV drugs are: Xanax, Soma, Darvon, Darvocet, Valium, Ativan, Talwin, Ambien, Tramadol.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Tramadol is a synthetic opioid used for pain relief. It causes sedation and has mild stimulant effects, acting as a downer. Short-term use is effective for managing pain, but long-term use can lead to dependence, tolerance, and health issues. Overdose risks include respiratory depression and seizures. Safe use involves following prescribed dosages and monitoring for side effects. Recent research focuses on its efficacy and compares its risks with other opioids.  |
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VII. Psychological Effects
Tramadol, an opioid, affects serotonin and norepinephrine systems, causing euphoria and cognitive impairment. Immediate effects include mood enhancement and pain relief, lasting several hours. Long-term use can lead to dependence and psychological issues such as depression. Research indicates significant mental health risks with chronic use, including severe mood disturbances and potential for addiction.
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VIII. Culture
Tramadol is a synthetic opioid used for pain management, with no significant historical or cultural lore. It gained prominence in the late 20th century as a pain medication. Modern cultural discussions focus on its benefits for pain relief versus its potential for dependence and abuse. Proponents emphasize its effectiveness and accessibility, while opponents warn of addiction risks. Its use is primarily medicinal, reflecting broader themes in pain management and the ongoing opioid crisis.
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